Article
A genome-wide screen for association in Hungarian multiple sclerosis.
Journal of neuroimmunology - 1 Oct 2003
Rajda Cecilia, Bencsik Krisztina, Seres Erika, Jonasdottir Aslaug, Foltynie Thomas, Sawcer Stephen, Benediktsson Kjartan, Fossdal Ragnheidur, Setakis Efrosini, Compston Alastair, Vécsei László
Abstract excerpt
Although the pathogenesis of multiple sclerosis (MS) is not fully understood, substantial evidence points to the involvement of genetic factors. We report on a genome-wide screen for disease association in the Hungarian population using 5532 microsatellite markers. These markers were typed in DNA pools that consisted of 88 MS patients (cases), and 128 unrelated controls. Based on a stringent selection criterion,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
