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Article

Genetic determinants of neuronal vulnerability to apoptosis.

Cellular and molecular life sciences : CMLS - 1 Jan 2013

Almeida Angeles

Abstract excerpt

Apoptosis is a common mode of cell death that contributes to neuronal loss associated with neurodegeneration. Single-nucleotide polymorphisms (SNPs) in chromosomal DNA are contributing factors dictating natural susceptibility of humans to disease. Here, the most common SNPs affecting neuronal vulnerability to apoptosis are reviewed in the context of neurological disorders. Polymorphic variants in genes encoding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22695677
DOI: 10.1007/s00018-012-1029-y
PMCID: PMC11113535

Genes

BAX
BCL2
CASP3
CASP8
CASP9
FAS
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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