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Article

Candidate gene study of TRAIL and TRAIL receptors: association with response to interferon beta therapy in multiple sclerosis patients.

PloS one - 1 Jan 2013

López-Gómez Carlos, Pino-Ángeles Almudena, Órpez-Zafra Teresa, Pinto-Medel María Jesús, Oliver-Martos Begoña, Ortega-Pinazo Jesús, Arnáiz Carlos, Guijarro-Castro Cristina, Varadé Jezabel, Álvarez-Lafuente Roberto, Urcelay Elena, Sánchez-Jiménez Francisca, Fernández Óscar, Leyva Laura

Abstract excerpt

TRAIL and TRAIL Receptor genes have been implicated in Multiple Sclerosis pathology as well as in the response to IFN beta therapy. The objective of our study was to evaluate the association of these genes in relation to the age at disease onset (AAO) and to the clinical response upon IFN beta treatment in Spanish MS patients. We carried out a candidate gene study of TRAIL, TRAILR-1, TRAILR-2, TRAILR-3 and...

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Identifiers

PMID: 23658636
DOI: 10.1371/journal.pone.0062540
PMCID: PMC3639207

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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