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Article

Investigation of bax, bcl-2, bcl-x and p53 gene polymorphisms in multiple sclerosis.

Journal of neuroimmunology - 1 Aug 2002

Kuhlmann T, Glas M, zum Bruch C, Mueller W, Weber A, Zipp F, Brück W

Abstract excerpt

Clinical course, outcome, radiological features, severity, and histopathology are heterogenous in multiple sclerosis (MS). Since MS is considered to be a polygenic disease, the genetic background may at least partly be responsible for this variability. Some MS cases are histopathologically characterized by a dramatic oligodendrocyte loss that is in part caused by apoptosis. A dysregulated apoptotic elimination of...

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PMID: 12161031
DOI: 10.1016/s0165-5728(02)00167-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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