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Article

TRAIL/TRAIL receptor system and susceptibility to multiple sclerosis.

PloS one - 1 Jan 2011

López-Gómez Carlos, Fernández Oscar, García-León Juan Antonio, Pinto-Medel María Jesús, Oliver-Martos Begoña, Ortega-Pinazo Jesús, Suardíaz Margarita, García-Trujillo Lucía, Guijarro-Castro Cristina, Benito-León Julián, Prat Isidro, Varadé Jezabel, Álvarez-Lafuente Roberto, Urcelay Elena, Leyva Laura

Abstract excerpt

The TNF-related apoptosis inducing ligand (TRAIL)/TRAIL receptor system participates in crucial steps in immune cell activation or differentiation. It is able to inhibit proliferation and activation of T cells and to induce apoptosis of neurons and oligodendrocytes, and seems to be implicated in autoimmune diseases. Thus, TRAIL and TRAIL receptor genes are potential candidates for involvement in susceptibility to...

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Identifiers

PMID: 21814551
DOI: 10.1371/journal.pone.0021766
PMCID: PMC3140982

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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TRAIL/TRAIL receptor system and susceptibility to multiple sclerosis.PMID 21814551Read ↗

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