Article
Analysis of 45 candidate genes for disease modifying activity in multiple sclerosis.
Journal of neurology - 1 Aug 2008
Ramagopalan Sreeram V, Deluca Gabriele C, Morrison Katie M, Herrera Blanca M, Dyment David A, Lincoln Matthew R, Orton Sarah-Michelle, Chao Michael J, Degenhardt Alexandra, Pugliatti Maura, Sadovnick A Dessa, Sotgiu Stefano, Ebers George C
Abstract excerpt
Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system unsurpassed for its variability in disease outcome. As little is conclusively known about MS disease mechanisms, we have selected a variety of candidate genes that may influence the prognosis of the disease based on their function. A cohort of sporadic MS cases, taken from opposite extremes of the putative distribution of...
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