Article
Interleukin-1 receptor antagonist gene polymorphism in human colorectal cancer.
Oncology reports - 1 Oct 2005
Viet Hung Trinh, Wågsäter Dick, Hugander Anders, Dimberg Jan
Abstract excerpt
Several studies indicate that local immunoregulation and associated cytokines have a putative role in the development of cancer. There is evidence that pro-inflammatory cytokines such as interleukin-1 (IL-1) are critically involved with tumour progression. IL-1 receptor antagonist (IL-1Ra) is known to down-regulate and limit the inflammatory response. Therefore we attempted to examine the influence of the known...
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