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Article

Polymorphism of IL-1 receptor antagonist gene: role in cancer.

Anticancer research - 1 Jan 2000

Sehouli Jalid, Mustea Alexander, Könsgen Dominique, Katsares Ioanna, Lichtenegger Werner

Abstract excerpt

BACKGROUND: IL-1-cytokines are strongly involved in carcinogenesis and tumor genesis. In this systematic review we will describe the role of IL-1 RA within the cytokine network and its predictive and prognostic value in cancer. MATERIALS AND METHODS: We analysed preclinical and clinical studies. RESULTS: A polymorphism is present in intron 2 of the human IL-1RA gene. The IL-1RA allele 2 has an influence on the...

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PMID: 12530098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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