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Article

Interleukin-1 receptor antagonist VNTR-polymorphism in inflammatory bowel disease.

Genes and immunity - 1 Nov 2002

Vijgen L, Van Gysel M, Rector A, Thoelen I, Esters N, Ceelen T, Vangoidsenhoven E, Vermeire S, Rutgeerts P, Van Ranst M

Abstract excerpt

Both genetic and environmental factors have been implicated in the etiology of inflammatory bowel diseases (IBD) i.e., Crohn's disease (CD) and ulcerative colitis (UC). Polymorphisms in cytokine genes are likely to influence an individual's predisposition to IBD. In intron 2 of the interleukin-1 receptor antagonist (IL-1ra) gene, a variable number of an 86-bp tandem repeat (VNTR) polymorphism leads to the...

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PMID: 12424621
DOI: 10.1038/sj.gene.6363888

Genes

NOD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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