Article
Interleukin-1 receptor antagonist gene polymorphism in patients with rheumatoid arthritis in India.
The Indian journal of medical research - 1 Jun 2006
Grover S, Tandon S, Misra R, Aggarwal A
Abstract excerpt
BACKGROUND & OBJECTIVES: Interleukin-1 receptor antagonist (IL-1Ra) is a naturally occurring anti-inflammatory molecule that blocks action of IL-1. Polymorphism in IL-1Ra gene intron 2 results in differences in production of IL-1Ra. These polymorphisms are reportedly associated with autoimmune disease susceptibility in different studies. However, such data are lacking from India. We undertook this study to...
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