Article
Interleukin-1 receptor antagonist gene polymorphism in epithelial ovarian cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2003
Sehouli Jalid, Mustea Alexander, Koensgen Dominique, Lichtenegger Werner
Abstract excerpt
The development of malignant tumors is constituted by different immunological components. Interleukin (IL)-1 receptor antagonist (RA) is known to be critically involved in the carcinogenesis of different malignant solid tumors. Polymorphism of a specific gene can have an important effect on gene transcription, the stability of the mRNA, or the quantity and activity of the resulting protein. In a case-control...
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