Article
Significant differences in the interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms in a Hungarian population with inflammatory bowel disease.
Scandinavian journal of gastroenterology - 1 Feb 1999
Nemetz A, Köpe A, Molnár T, Kovács A, Fehér J, Tulassay Z, Nagy F, García-González M A, Peña A S
Abstract excerpt
BACKGROUND: There is growing evidence of the importance of genetic predisposition and the activation of the mucosal immune system in the pathogenesis of inflammatory bowel disease. Thus, genes involved in the regulation of inflammation are receiving increased attention. We have studied whether Crohn's disease (CD) or ulcerative colitis (UC) is associated with certain allelic combinations of IL1B/IL1RA gene...
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