Significance of interleukin-1beta and interleukin-1 receptor antagonist genetic polymorphism in inflammatory bowel diseases.

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Article

Significance of interleukin-1beta and interleukin-1 receptor antagonist genetic polymorphism in inflammatory bowel diseases.

The American journal of gastroenterology - 1 Jul 1997

Heresbach D, Alizadeh M, Dabadie A, Le Berre N, Colombel J F, Yaouanq J, Bretagne J F, Semana G

Abstract excerpt

OBJECTIVE: Genetic susceptibility to inflammatory bowel disease is well recognized. There is also increasing evidence for the activation of the mucosal immune system and the production of inflammatory cytokines, i.e., interleukin (IL)-1ra and IL-1beta in the inflammatory bowel disease. The aim of...

Topics

Adult
Alleles
Colitis, Ulcerative
Crohn Disease
Female
Humans
Inflammatory Bowel Diseases
Interleukin-1
Male
Polymorphism, Genetic
Receptors, Interleukin
Severity of Illness Index

Source

Open in PubMed

Identifiers

PMID: 9219791

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9219791-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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