Article
Association of the interleukin 1 receptor antagonist gene with ulcerative colitis in Northern European Caucasians.
Gut - 1 Apr 2001
Carter M J, di Giovine F S, Jones S, Mee J, Camp N J, Lobo A J, Duff G W
Abstract excerpt
BACKGROUND AND AIMS: An association between the allele 2 of the interleukin 1 receptor antagonist gene variable number tandem repeats polymorphism in intron 2 and ulcerative colitis was first reported in 1994. Subsequent studies in Caucasian Northern European patients have not confirmed this, although trends towards an association were observed. The lack of statistical significance could reflect inadequate power....
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