Article
Interleukin-1 receptor antagonist gene polymorphism is associated with increased risk of epithelial ovarian cancer.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Oct 2003
Sehouli J, Mustea A, Koensgen D, Chen F C-K, Lichtenegger W
Abstract excerpt
BACKGROUND: Different studies indicate that immunological components play a key role in the development of cancer. Interleukin-1 (IL-1) is known to be critically involved in ovarian carcinogenesis and in other solid tumors. Therefore, we investigated the possible influence of the polymorphism of the IL-1 receptor antagonist (IL-1 RA) genes on the development of ovarian cancer. PATIENTS AND METHODS: In a...
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