Article
Mei-S332, a Drosophila protein required for sister-chromatid cohesion, can localize to meiotic centromere regions.
Cell - 20 Oct 1995
Kerrebrock A W, Moore D P, Wu J S, Orr-Weaver T L
Abstract excerpt
Mutations in the Drosophila mei-S332 gene cause premature separation of the sister chromatids in late anaphase of meiosis I. Therefore, the mei-S332 protein was postulated to hold the centromere regions of sister chromatids together until anaphase II. The mei-S332 gene encodes a novel 44 kDa protein. Mutations in mei-S332 that differentially affect function in males or females map to distinct domains of the...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Cycle Proteins
- Centromere
- Chromatids
- Chromosome Walking
- Chromosomes
- Cloning, Molecular
- Drosophila
- Drosophila Proteins