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Article

Drosophila GABA(B) receptors are involved in behavioral effects of gamma-hydroxybutyric acid (GHB).

European journal of pharmacology - 20 Sept 2005

Dimitrijevic Nikola, Dzitoyeva Svetlana, Satta Rosalba, Imbesi Marta, Yildiz Sevim, Manev Hari

Abstract excerpt

Gamma-hydroxybutyric acid (GHB) can be synthesized in the brain but is also a known drug of abuse. Although putative GHB receptors have been cloned, it has been proposed that, similar to the behavior-impairing effects of ethanol, the in vivo effects of pharmacological GHB may involve metabotropic gamma-aminobutyric acid (GABA) GABA(B) receptors. We developed a fruitfly (Drosophila melanogater) model to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 16129424
DOI: 10.1016/j.ejphar.2005.07.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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