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Article

Pharmacological evidence for GABAergic regulation of specific behaviors in Drosophila melanogaster.

Journal of neurobiology - 15 Feb 2002

Leal Sandra M, Neckameyer Wendi S

Abstract excerpt

We have identified several GABAergic-modulated behaviors in Drosophila melanogaster by employing a pharmacological approach to disrupt GABA transporter function in vivo. Systemic treatment of adult female flies with the GABA transport inhibitors DL-2,4-diaminobutyric acid (DABA) or R,S-nipecotic acid (NipA), resulted in diminished locomotor activity, deficits in geotaxis, and the induction of convulsive behaviors...

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Identifiers

PMID: 11810639
DOI: 10.1002/neu.10030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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