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Article

Functional ethanol tolerance in Drosophila.

Neuron - 1 Oct 2000

Scholz H, Ramond J, Singh C M, Heberlein U

Abstract excerpt

In humans, repeated alcohol consumption leads to the development of tolerance, manifested as a reduced physiological and behavioral response to a particular dose of alcohol. Here we show that adult Drosophila develop tolerance to the sedating and motor-impairing effects of ethanol with kinetics of acquisition and dissipation that mimic those seen in mammals. Importantly, this tolerance is not caused by changes in...

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PMID: 11086999
DOI: 10.1016/s0896-6273(00)00101-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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