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Article

Glycine receptors containing α2 or α3 subunits regulate specific ethanol-mediated behaviors.

The Journal of pharmacology and experimental therapeutics - 1 Apr 2015

Blednov Yuri A, Benavidez Jillian M, Black Mendy, Leiter Courtney R, Osterndorff-Kahanek Elizabeth, Harris R Adron

Abstract excerpt

Glycine receptors (GlyRs) are broadly expressed in the central nervous system. Ethanol enhances the function of brain GlyRs, and the GlyRα1 subunit is associated with some of the behavioral actions of ethanol, such as loss of righting reflex. The in vivo role of GlyRα2 and α3 subunits in alcohol responses has not been characterized despite high expression levels in the nucleus accumbens and amygdala, areas that...

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Identifiers

PMID: 25678534
DOI: 10.1124/jpet.114.221895
PMCID: PMC4366753

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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