Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic control of acute ethanol-induced behaviors in Drosophila.

Alcoholism, clinical and experimental research - 1 Aug 2000

Singh C M, Heberlein U

Abstract excerpt

BACKGROUND: In most organisms in which acute ethanol exposure has been studied, it leads to similar changes in behavior. Generally, low ethanol doses activate the central nervous system, whereas high doses are sedative. Sensitivity to the acute intoxicating effects of ethanol is in part under genetic control in rodents and humans, and reduced sensitivity in humans predicts the development of alcoholism (Crabbe et...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Absorption
Share to Behavior, Animal
Share to Drosophila melanogaster

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance

Share to Ethanol

Share to Kinetics

Share to Motor Activity

Share to Mutation

Source

Identifiers

PMID: 10968649

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic control of acute ethanol-induced behaviors in Drosophila.PMID 10968649Read ↗

Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogaster.Semantic proximity Read ↗

Ethanol intoxication in Drosophila: Genetic and pharmacological evidence for regulation by the cAMP signaling pathway.Semantic proximity Read ↗

The Evolution of Drosophila melanogaster as a Model for Alcohol ResearchSemantic proximity Read ↗

An Assay for Measuring the Effects of Ethanol on the Locomotion Speed of Caenorhabditis elegans.Semantic proximity Read ↗

Drosophila melanogaster, a genetic model system for alcohol research.Semantic proximity Read ↗

Ethanol-regulated genes that contribute to ethanol sensitivity and rapid tolerance in Drosophila.Semantic proximity Read ↗

High-resolution analysis of ethanol-induced locomotor stimulation in Drosophila.Semantic proximity Read ↗

Large analysis of genetic manipulations reveals an inverse correlation between initial alcohol resistance and rapid tolerance phenotypes.Semantic proximity Read ↗

Screening for ENU-induced mutations in mice that result in aberrant ethanol-related phenotypes.Semantic proximity Read ↗

Functional ethanol tolerance in Drosophila.Semantic proximity Read ↗

Large genetic analysis of alcohol resistance and tolerance reveals an inverse correlation and suggests ‘true’ tolerance mutantsSemantic proximity Read ↗

REVIEW: Alcohol‐related genes: contributions from studies with genetically engineered miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.