Article
Contribution of the amino and carboxyl termini for PHA-4/FoxA function in Caenorhabditis elegans.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Oct 2005
Kaltenbach Linda S, Updike Dustin L, Mango Susan E
Abstract excerpt
FoxA transcription factors are central regulators of gut development in all animals that have been studied. Here we examine the sole Caenorhabditis elegans FoxA protein, which is called pha-4. We describe the molecular characterization of five pha-4 mutations and characterize their associated phenotypes. Two nonsense mutations are predicted to truncate PHA-4 after the DNA binding domain and remove the conserved...
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