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Article

Alteration of the DNA binding domain disrupts distinct functions of the C. elegans Pax protein EGL-38.

Mechanisms of development - 1 Jul 2005

Zhang Guojuan, Sleiman Sama F, Tseng Rong-Jeng, Rajakumar Vandana, Wang Xiaodong, Chamberlin Helen M

Abstract excerpt

The paired-domain-containing Pax transcription factors play an important role in the development of a range of organ, tissue and cell types. Although DNA binding elements and target genes for Pax proteins have been identified, how these proteins identify appropriate DNA elements and regulate different genes in different cellular contexts is not well understood. To investigate the relationship between Pax proteins...

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PMID: 15923112
DOI: 10.1016/j.mod.2005.04.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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