Article
The pha-4 gene is required to generate the pharyngeal primordium of Caenorhabditis elegans.
Development (Cambridge, England) - 1 Oct 1994
Mango S E, Lambie E J, Kimble J
Abstract excerpt
In the 4-cell Caenorhabditis elegans embryo, two blastomeres are destined to generate pharyngeal cells, each by a distinct developmental strategy: one pathway is inductive, while the other is autonomous. Here, we identify the pha-4 locus. In animals lacking pha-4 activity, an early step in pharyngeal organogenesis is blocked: no pharyngeal primordium is formed and differentiated pharyngeal cells are absent. Most...
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