Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging.

Current biology : CB - 23 Sept 2008

Sheaffer Karyn L, Updike Dustin L, Mango Susan E

Abstract excerpt

BACKGROUND: FoxA factors are critical regulators of embryonic development and postembryonic life, but little is know about the upstream pathways that modulate their activity. C. elegans pha-4 encodes a FoxA transcription factor that is required to establish the foregut in embryos and to control g...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Caenorhabditis elegans Proteins
Share to Larva

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Longevity

Share to Phosphotransferases (Alcohol Group Acceptor)

Share to Ribonucleoproteins

Share to RNA Interference

Source

Open in PubMed Open full text

Identifiers

PMID: 18804378
DOI: 10.1016/j.cub.2008.07.097
PMCID: PMC2615410

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18804378-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging.PMID 18804378Read ↗

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action.Semantic proximity Read ↗

<i>jouvence</i> , a new small nucleolar RNA required in the gut extends lifespan in DrosophilaSemantic proximity Read ↗

Contribution of the amino and carboxyl termini for PHA-4/FoxA function in Caenorhabditis elegans.Semantic proximity Read ↗

Drosophila TIF-IA is required for ribosome synthesis and cell growth and is regulated by the TOR pathway.Semantic proximity Read ↗

The Drosophila FoxA ortholog Fork head regulates growth and gene expression downstream of Target of rapamycin.Semantic proximity Read ↗

The adaptor-like protein ROG-1 is required for activation of the Ras-MAP kinase pathway and meiotic cell cycle progression in Caenorhabditis elegans.Semantic proximity Read ↗

Vitamin B <sub>12</sub> alleviates Verheij syndrome-like defects via phospholipid remodeling in a <i>C. elegans</i> PUF60 spliceosomopathy modelSemantic proximity Read ↗

The coordinate regulation of pharyngeal development in C. elegans by lin-35/Rb, pha-1, and ubc-18.Semantic proximity Read ↗

A mitochondrial unfolded protein response-independent role of DVE-1 in longevity regulation.Semantic proximity Read ↗

Genome‐wide screen identifies signaling pathways that regulate autophagy during Caenorhabditis elegans developmentSemantic proximity Read ↗

Ribosome biogenesis protein Urb1 acts downstream of mTOR complex 1 to modulate digestive organ development in zebrafish.Semantic proximity Read ↗

Ribosomal protein RPS-14 modulates let-7 microRNA function in Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.