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Article

Regulation of organogenesis by the Caenorhabditis elegans FoxA protein PHA-4.

Science (New York, N.Y.) - 1 Feb 2002

Gaudet J, Mango S E

Abstract excerpt

The pha-4 locus encodes a forkhead box A (FoxA/HNF3) transcription factor homolog that specifies organ identity for Caenorhabditis elegans pharyngeal cells. We used microarrays to identify pharyngeal genes and analyzed those genes to determine which were direct PHA-4 targets. Our data suggest that PHA-4 directly activates most or all pharyngeal genes. Furthermore, the relative affinity of PHA-4 for different...

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Identifiers

PMID: 11823633
DOI: 10.1126/science.1065175

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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