Article
A regulatory module controlling pharyngeal development and function in Caenorhabditis elegans.
Genetics - 1 Jul 2012
Fay David S, Polley Stanley R G, Kuang Jujiao, Kuzmanov Aleksandra, Hazel James W, Mani Kumaran, Veo Bethany L, Yochem John
Abstract excerpt
In Caenorhabditis elegans, the differentiation and morphogenesis of the foregut are controlled by several transcriptional regulators and cell signaling events, and by PHA-1, an essential cytoplasmic protein of unknown function. Previously we have shown that LIN-35 and UBC-18-ARI-1 contribute to the regulation of pha-1 and pharyngeal development through the Zn-finger protein SUP-35/ZTF-21. Here we characterize...
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