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Article

Transcription factor NFY globally represses the expression of the C. elegans Hox gene Abdominal-B homolog egl-5.

Developmental biology - 15 Aug 2007

Deng Hansong, Sun Yinyan, Zhang Yuxia, Luo Xin, Hou Wenru, Yan Libo, Chen Yaoyao, Tian E, Han Jinghua, Zhang Hong

Abstract excerpt

The C. elegans Hox gene egl-5 (ortholog of Drosophila Abdominal-B) is expressed in multiple tissues in the tail region and is involved in tail patterning. In this study, we identify and clone the corresponding C. elegans orthologs of the components of the heterotrimeric transcription factor NFY, nfya-1, nfyb-1 and nfyc-1 and demonstrate that mutations in these components result in the ectopic expression of egl-5...

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Source

Identifiers

PMID: 17574230
DOI: 10.1016/j.ydbio.2007.05.021

Genes

NFYA
NFYB
NFYC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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