Article
Regulation of cell fate in Caenorhabditis elegans by a novel cytoplasmic polyadenylation element binding protein.
Developmental biology - 15 Jan 2001
Jin S W, Kimble J, Ellis R E
Abstract excerpt
The fog-1 gene of Caenorhabditis elegans specifies that germ cells differentiate as sperm rather than as oocytes. We cloned fog-1 through a combination of transformation rescue experiments, RNA-mediated inactivation, and mutant analyses. Our results show that fog-1 produces two transcripts, both of which are found in germ cells but not in the soma. Furthermore, two deletion mutants alter these transcripts and are...
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