Article
No association found between 158 Val/Met polymorphism of the COMT gene and schizophrenia with minor physical anomalies.
Psychiatry research - 15 Sept 2005
Joo Eun-Jeong, Jeong Seong-Hoon, Ahn Yong-Min, Lee Kyu-Young, Chang Yoon Se, Kim Eui-Joong, Kim Seon-Uk, Cho Soo-Churl, Sik Kim Yong
Abstract excerpt
The catechol-O-methyl transferase (COMT) gene has been a promising candidate in genetic research on schizophrenia because of its function in dopamine metabolism and its location on chromosome 22q11.2, which may be implicated in both schizophrenia and velocardiofacial syndrome (VCFS). To explore the possible genetic contribution of COMT to the development of schizophrenia, we focused on the subgroup of patients...
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