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Article

No association of functional polymorphisms in methlylenetetrahydrofolate reductase and the risk and minor physical anomalies of schizophrenia in Korean population.

Journal of Korean medical science - 1 Oct 2011

Kim Su-Gyeong, Song Joo Yun, Joo Eun-Jeong, Jeong Seong Hoon, Kim Se Hyun, Lee Kyu Young, Lee Nam Young, Ahn Yong Min, Kim Yong Sik, Roh Myoung-Sun

Abstract excerpt

Methylenetetrahydrofolate reductase (MTHFR), a critical enzyme in folate metabolism, plays an important role in DNA methylation. It has been suggested that abnormal DNA methylation contributes to the pathogenesis of schizophrenia and congenital anomalies. The previous findings regarding the genetic relationship between MTHFR and schizophrenia are controversial. This study investigated the association of the two...

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Identifiers

PMID: 22022190
DOI: 10.3346/jkms.2011.26.10.1356
PMCID: PMC3192349

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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