Article
COMT Val(158)Met and BDNF C(270)T polymorphisms in schizophrenia: a case-control study.
Schizophrenia research - 1 Feb 2005
Galderisi Silvana, Maj Mario, Kirkpatrick Brian, Piccardi Paola, Mucci Armida, Invernizzi Giordano, Rossi Alessandro, Pini Stefano, Vita Antonio, Cassano Paolo, Stratta Paolo, Severino Giovanni, Del Zompo Maria
Abstract excerpt
In a multicenter study involving 217 subjects of European ancestry [106 patients with schizophrenia and 111 healthy subjects], we tested the hypothesis that the catechol-O-methyl transferase (COMT) Val(158)Met and/or the brain-derived neurotrophic factor (BDNF) C(270)T gene polymorphisms are associated with schizophrenia. The COMT and BDNF genotype and their allele distribution did not differ between patients...
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