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Article

Systematic mutation analysis of the catechol O-methyltransferase gene as a candidate gene for schizophrenia.

The American journal of psychiatry - 1 Aug 1999

Chen C H, Lee Y R, Chung M Y, Wei F C, Koong F J, Shaw C K, Yeh J I, Hsiao K J

Abstract excerpt

OBJECTIVE: Catechol O-methyltransferase (COMT) is involved in the degradation of catecholamine neurotransmitters. Recent linkage studies of schizophrenia and molecular studies of velocardiofacial syndrome suggest that the COMT gene might be a candidate gene for schizophrenia. METHOD: The authors...

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Source

Identifiers

PMID: 10450274
DOI: 10.1176/ajp.156.8.1273

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10450274-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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