Article
Identification of hepatitis B virus X gene variants between hepatocellular carcinoma tissues and pericarcinoma liver tissues in Eastern China.
International journal of clinical and experimental pathology - 1 Jan 2014
Wang Dan, Cai Hao, Yu Wen-Bo, Yu Long
Abstract excerpt
UNLABELLED: Hepatocellular carcinoma (HCC) is one of the most malignant tumors worldwide, especially in Eastern China where HBV infection confirmed as the most important pathological element. HBV X gene, extremely easy to mutate and integrate into hepatocytes, plays a significant role in HBV infection and HCC development. We deduced that mutations of integrated HBx gene make transformation more malignant. The aim...
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