Identification of hepatitis B virus X gene variants between hepatocellular carcinoma tissues and pericarcinoma liver tissues in Eastern China.

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Article

Identification of hepatitis B virus X gene variants between hepatocellular carcinoma tissues and pericarcinoma liver tissues in Eastern China.

International journal of clinical and experimental pathology - 1 Jan 2014

Wang Dan, Cai Hao, Yu Wen-Bo, Yu Long

Abstract excerpt

UNLABELLED: Hepatocellular carcinoma (HCC) is one of the most malignant tumors worldwide, especially in Eastern China where HBV infection confirmed as the most important pathological element. HBV X gene, extremely easy to mutate and integrate into hepatocytes, plays a significant role in HBV infection and HCC development. We deduced that mutations of integrated HBx gene make transformation more malignant. The aim...

Topics

Amino Acid Sequence
Carcinoma, Hepatocellular
Cell Transformation, Viral
China
DNA Mutational Analysis
DNA, Viral
Female
Genotype
Hepatitis B
Hepatitis B virus
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hydrophobic and Hydrophilic Interactions

Liver

Liver Neoplasms

Male

Mutation

Neoplasm Staging

Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 25337243
PMCID: PMC4203214

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