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Article

[Associations between hepatitis B virus x gene mutations and hepatocellular carcinoma].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Aug 2015

Wang Miao, Hu Yanfang, Shi Weitao, Wang Qinying

Abstract excerpt

OBJECTIVE: To investigate the association of mutations in the hepatitis B virus (HBV) X gene (HBX, encoding the HBx protein) and development of hepatocellular carcinoma (HCC). METHODS: Forty-four patients with HBV-related HCC participated in the study, along with 76 patients with chronic HBV infection who assessed as controls. All patients had serum HBV DNA levels that were higher than 10(3) copies/ml. Extracted...

Topics

Carcinoma, Hepatocellular
Hepatitis B e Antigens
Hepatitis B virus
Hepatitis B, Chronic
Humans
Incidence
Liver Neoplasms
Mutation
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26447624
DOI: 10.3760/cma.j.issn.1007-3418.2015.08.009
PMCID: PMC12814394

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-26447624-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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