Analysis of hepatitis B virus X gene (HBx) mutants in tissues of patients suffered from hepatocellular carcinoma in China.

doi:10.1016/j.canep.2011.11.006

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Article

Analysis of hepatitis B virus X gene (HBx) mutants in tissues of patients suffered from hepatocellular carcinoma in China.

Cancer epidemiology - 1 Aug 2012

Wang Qi, Zhang Tao, Ye Lihong, Wang Wenhui, Zhang Xiaodong

Abstract excerpt

Hepatitis B virus (HBV) X (HBx) gene multi-site mutations are a frequent event in the clinical hepatocellular carcinoma (HCC) tissues. It has been reported that the mutation of the HBx plays a crucial role in the development of HBV-related HCC. To identify the novel mutations of HBx in the HCC ti...

Topics

Adult
Aged
Amino Acid Sequence
Carcinoma, Hepatocellular
Female
Hepatitis B virus
Hepatitis B, Chronic
Humans
Liver Neoplasms
Male
Middle Aged
Molecular Sequence Data
Mutation
Trans-Activators
Viral Regulatory and Accessory Proteins
Young Adult

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Identifiers

PMID: 22178505
DOI: 10.1016/j.canep.2011.11.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-22178505-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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