Article
Polycomb group regulation of Hox gene expression in C. elegans.
Developmental cell - 1 Jun 2003
Ross Jennifer M, Zarkower David
Abstract excerpt
Polycomb group (PcG) chromatin proteins regulate homeotic genes in both animals and plants. In Drosophila and vertebrates, PcG proteins form complexes and maintain early patterns of Hox gene repression, ensuring fidelity of developmental patterning. PcG proteins in C. elegans form a complex and mediate transcriptional silencing in the germline, but no role for the C. elegans PcG homologs in somatic Hox gene...
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