Article
Transient requirements of YY1 expression for PcG transcriptional repression and phenotypic rescue.
Journal of cellular biochemistry - 1 Nov 2005
Srinivasan Lakshmi, Pan Xuan, Atchison Michael L
Abstract excerpt
A hallmark of PcG transcriptional repression is stability of the repressed state, although the mechanism of this stability is unclear. The mammalian transcription factor YY1 can function as a PcG protein in Drosophila resulting in transcriptional repression and correction of phenotypic defects caused by mutation of its homologue, Pleiohomeotic (PHO). To discern the temporal requirements of YY1 expression for...
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