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Article

Yin Yang 1, a vertebrate polycomb group gene, regulates antero-posterior neural patterning.

Biochemical and biophysical research communications - 11 Jul 2003

Kwon Hye-Joo, Chung Hae-Moon

Abstract excerpt

Polycomb group (PcG) genes are required for the stable repression of the homeotic genes and other developmentally regulated genes. Yin Yang 1 (YY1), a vertebrate homolog of the Drosophila PcG pleiohomeotic (Pho), is a multifunctional protein that can act as a repressor or activator of transcription. Xenopus YY1 (XYY1) protein was localized in the central nervous system (CNS), particularly anterior neural tube of...

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PMID: 12821143
DOI: 10.1016/s0006-291x(03)01071-4

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Yin Yang 1, a vertebrate polycomb group gene, regulates antero-posterior neural patterning.PMID 12821143Read ↗

Yin Yang 1 physically interacts with Hoxa11 and represses Hoxa11-dependent transcription.Semantic proximity Read ↗

Transcription factor YY1 functions as a PcG protein in vivo.Semantic proximity Read ↗

Misexpression of Polycomb-group proteins in Xenopus alters anterior neural development and represses neural target genes.Semantic proximity Read ↗

The polycomb group protein EED interacts with YY1, and both proteins induce neural tissue in Xenopus embryos.Semantic proximity Read ↗

Homeotic transformations of the axial skeleton of YY1 mutant mice and genetic interaction with the Polycomb group gene Ring1/Ring1A.Semantic proximity Read ↗

Yin Yang 1 is critical for mid-hindbrain neuroepithelium development and involved in cerebellar agenesis.Semantic proximity Read ↗

A role of polycomb group genes in the regulation of gap gene expression in Drosophila.Semantic proximity Read ↗

YY1 DNA binding and interaction with YAF2 is essential for Polycomb recruitment.Semantic proximity Read ↗

The pleiohomeotic functions as a negative regulator of Drosophila even-skipped gene during embryogenesis.Semantic proximity Read ↗

YY1 regulates the neural crest-associated slug gene in Xenopus laevis.Semantic proximity Read ↗

The polycomb group protein ring1b/rnf2 is specifically required for craniofacial development.Semantic proximity Read ↗

Widespread expression of the eve1 gene in zebrafish embryos affects the anterior-posterior axis pattern.Semantic proximity Read ↗

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