Article
Transcription factor YY1 functions as a PcG protein in vivo.
The EMBO journal - 17 Mar 2003
Atchison Lakshmi, Ghias Ayesha, Wilkinson Frank, Bonini Nancy, Atchison Michael L
Abstract excerpt
Polycomb group (PcG) proteins function as high molecular weight complexes that maintain transcriptional repression patterns during embryogenesis. The vertebrate DNA binding protein and transcriptional repressor, YY1, shows sequence homology with the Drosophila PcG protein, pleiohomeotic (PHO). YY1 might therefore be a vertebrate PcG protein. We used Drosophila embryo and larval/imaginal disc transcriptional...
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