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Article

YY1 DNA binding and PcG recruitment requires CtBP.

Genes & development - 1 Nov 2004

Srinivasan Lakshmi, Atchison Michael L

Abstract excerpt

We found that mammalian Polycomb group (PcG) protein YY1 can bind to Polycomb response elements in Drosophila embryos and can recruit other PcG proteins to DNA. PcG recruitment results in deacetylation and methylation of histone H3. In a CtBP mutant background, recruitment of PcG proteins and concomitant histone modifications do not occur. Surprisingly, YY1 DNA binding in vivo is also ablated. CtBP mutation does...

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Source

Open in PubMed Open full text

Identifiers

PMID: 15520279
DOI: 10.1101/gad.1228204
PMCID: PMC525539

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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