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Article

Distinct requirements for Pho, Sfmbt, and Ino80 for cell survival in Drosophila.

Genetics - 26 Aug 2021

Elizarev Pavel, Finkl Katja, Müller Jürg

Abstract excerpt

The Drosophila proteins Pleiohomeotic (Pho) and its paralog Pho-like (Phol) are the homologs of the mammalian transcription factor YY1. Pho and Phol are subunits of the Polycomb group protein complex PhoRC and they are also stably associated with the INO80 nucleosome remodeling complex. Drosophila lacking both Pho and Phol arrest development as larvae with small misshaped imaginal discs. The basis of this...

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Identifiers

PMID: 34849913
DOI: 10.1093/genetics/iyab096
PMCID: PMC8633127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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