Article
Prognostic role of cyclooxygenase-2 expression in esophageal carcinoma.
Cancer letters - 28 Jul 2005
Heeren Pierre, Plukker John, van Dullemen Hendrik, Nap Raoul, Hollema Harry
Abstract excerpt
Cyclooxygenase-2 (COX-2) is involved in esophageal carcinogenesis, but its clinical significance is not clarified yet. The association of several clinicopathological parameters with the immunohistochemical expression of COX-2 was analyzed in paraffin-embedded esophageal cancer specimens. In adenocarcinomas, COX-2 upregulation showed to be a late event and in a multivariate analysis it was associated independently...
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