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Article

Cyclooxygenase-2 mediated regulation of E-cadherin occurs in conventional but not early-onset gastric cancer cell lines.

Cellular oncology : the official journal of the International Society for Cellular Oncology - 1 Jan 2009

Sitarz R, Leguit R J, de Leng W W J, Morsink F H M, Polkowski W P, Maciejewski R, Offerhaus G J A, Milne A N

Abstract excerpt

BACKGROUND: COX-2 and E-cadherin, involved in invasion and metastasis, are molecules critical for gastric carcinogenesis. A relationship between them is documented in non-small cell lung and prostate cancer. We present novel evidence of a relationship between COX-2 and E-cadherin expression in gastric cancer. METHODS: Using qPCR and Western blots analysis on celecoxib and PGE2 treated and untreated gastric cancer...

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Identifiers

PMID: 19940363
DOI: 10.3233/CLO-2009-0496
PMCID: PMC4619102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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