Article
Overexpression of Cyclooxygenase-2 Is Associated with a Favorable Prognostic Phenotype in Breast Carcinoma
1 Jan 2005
Abstract excerpt
OBJECTIVES: Cyclooxygenase (COX) is the rate-limiting enzyme that catalyzes the conversion of arachidonic acid to prostaglandins. The purpose of the present study was to investigate the involvement of COX-2 protein in breast cancer biological behavior through its correlation with the well-known clinicopathological parameters and the expression of p53, c-erbB-2, topoisomerase IIalpha (topoIIalpha) and peroxisome...
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