Article
Immunohistochemical COX-2 overexpression correlates with HER-2/neu overexpression in invasive breast carcinomas: a pilot study.
Pathology, research and practice - 15 Mar 2011
Çiriş Ibrahim Metin, Bozkurt Kemal Kürşat, Başpinar Sirin, Kapucuoğlu Fatma Nilgün
Abstract excerpt
Cyclooxygenase-2 (COX-2) is a prostaglandin synthase that catalyzes the synthesis of prostaglandin G2 and H2. It has been shown that COX-2 plays an important role in tumorigenesis of different tumor types and it is thought to take part in breast carcinogenesis. In the present study, we aimed to investigate the relationship of immunohistochemical COX-2 expression with clinicopathological parameters, including...
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