Article
Cyclo-oxygenase-2 over-expression is associated with human esophageal squamous cell carcinoma.
Journal of Nippon Medical School = Nippon Ika Daigaku zasshi - 1 Dec 2006
Miyashita Masao, Makino Hiroshi, Katsuta Miwako, Nomura Tsutomu, Shinji Seiichi, Kashiwabara Moto, Takahashi Ken, Kudo Mitsuhiro, Ishiwata Toshiyuki, Naito Zenya, Tajiri Takashi
Abstract excerpt
Cyclo-oxygenase (COX)-2 is not usually detectable in normal tissues but is induced in inflammation and carcinogenesis. The level of COX-2 is elevated in cancer tissues of the colon, bladder, and skin. In the esophagus, squamous cell carcinoma and adenocarcinoma are known to express COX-2. The purpose of this study was to clarify the association of COX-2 expression with clinicopathological factors of squamous cell...
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