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Article

CTLA-4 gene polymorphisms in Chinese patients with ulcerative colitis.

Inflammatory bowel diseases - 1 Jul 2005

Hou Wei, Xia Bing, Yuan Anlong, Li Jin, Yang Zhanqiu, Mao Lin

Abstract excerpt

BACKGROUND: Ulcerative colitis (UC) is characterized by chronic inflammation of the colon and rectum as a result of an exaggerated T-cell response. Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) is a T cell-restricted surface molecule induced with TCR or CD28 activation. There is evidence for genetic involvement of CTLA-4 in several autoimmune diseases, with the focus on the possible role of genetic...

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Identifiers

PMID: 15973119
DOI: 10.1097/01.mib.0000165112.25934.36

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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