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Association of CTLA-4 variants with susceptibility to inflammatory bowel disease: a meta-analysis.

Human immunology - 1 Mar 2014

Zhang Min, Ni Jing, Xu Wang-Dong, Wen Peng-Fei, Qiu Li-Juan, Wang Xiao-Song, Pan Hai-Feng, Ye Dong-Qing

Abstract excerpt

OBJECTIVE: The aim of this study was to determine whether CTLA-4 gene variants were associated with susceptibility to inflammatory bowel disease (IBD). METHODS: Meta-analysis was conducted on the association between CTLA-4 variants and IBD using: (1) allelic contrast, (2) the recessive model, and (3) the dominant model. RESULTS: A total of 9 relevant studies including 1739 Crohn's disease (CD) cases, 10 relevant...

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Asian People
CTLA-4 Antigen
Gene Frequency
Genetic Predisposition to Disease
Inflammatory Bowel Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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PMID: 24374044
DOI: 10.1016/j.humimm.2013.12.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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