Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

CTLA4 gene polymorphisms in Dutch and Chinese patients with inflammatory bowel disease.

Scandinavian journal of gastroenterology - 1 Nov 2002

Xia B, Crusius J B A, Wu J, Zwiers A, van Bodegraven Ad A, Peña A S

Abstract excerpt

BACKGROUND: Inflammatory bowel diseases (IBDs) are characterized by chronic intestinal inflammation as a result of an exaggerated T-cell response. CTLA4, a receptor of activated T cells, has an inhibitory function in regulating T-cell activation. Since CTLA4 gene polymorphisms have been associated with several autoimmune diseases, the aim was to study these gene polymorphisms in patients with IBD in two different...

Topics

Join the communities discussing this publication.

Abatacept
Antigens, Differentiation
Colitis, Ulcerative
Crohn Disease
CTLA-4 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunoconjugates

Inflammatory Bowel Diseases

Source

Identifiers

PMID: 12465728
DOI: 10.1080/003655202761020579

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CTLA4 gene polymorphisms in Dutch and Chinese patients with inflammatory bowel disease.PMID 12465728Read ↗

CTLA-4 gene polymorphisms in Chinese patients with ulcerative colitis.Semantic proximity Read ↗

CTLA-4 polymorphisms and susceptibility to inflammatory bowel disease: a meta-analysis.Semantic proximity Read ↗

Analysis of cytotoxic T lymphocyte associated antigen 4 gene polymorphisms in patients with ulcerative colitis.Semantic proximity Read ↗

Association of CTLA-4 variants with susceptibility to inflammatory bowel disease: a meta-analysis.Semantic proximity Read ↗

Association of polymorphic alleles of CTLA4 with inflammatory bowel disease in the Japanese.Semantic proximity Read ↗

Association of CTLA-4 gene microsatellite polymorphism with ulcerative colitis in Chinese patients.Semantic proximity Read ↗

CTLA4 CT60 single-nucleotide polymorphism is associated with Slovenian inflammatory bowel disease patients and regulates expression of CTLA4 isoforms.Semantic proximity Read ↗

No association of the cytotoxic T-lymphocyte associated gene CTLA4 +49A/G polymorphisms with Crohn's disease and ulcerative colitis in Hungarian population samples.Semantic proximity Read ↗

[Toll-like receptor gene polymorphisms and susceptibility to inflammatory bowel disease in Chinese Han and Caucasian populations].Semantic proximity Read ↗

Cytotoxic T lymphocyte antigen-4 promoter -658CT gene polymorphism is associated with ulcerative colitis in Chinese patients.Semantic proximity Read ↗

Association of interleukin-17F 7488 single nucleotide polymorphism and inflammatory bowel disease in the Chinese population.Semantic proximity Read ↗

Investigation of CTLA-4 and CD28 gene polymorphisms in a group of Turkish patients with colorectal cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.